Understanding the brain circuits involved in binge drinking

CRF NEURAL CIRCUITS OF BINGE DRINKING

NIH-funded research University of Illinois at Chicago · NIH-10705320

This study is looking at how certain brain pathways affect binge drinking, with the hope of finding new ways to help people who struggle with alcohol use.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project IDNIH-10705320 on NIH RePORTER

What this research studies

This research investigates how specific brain circuits influence excessive binge drinking behavior. By focusing on the role of corticotropin-releasing factor (CRF) in the brain, the study aims to identify the neural pathways that contribute to binge alcohol consumption. Researchers will employ advanced techniques such as optogenetics and electrophysiology to observe how these circuits operate during binge drinking episodes. The goal is to uncover mechanisms that could lead to new treatments for individuals struggling with alcohol use disorders.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who engage in binge drinking behaviors and are seeking help to reduce their alcohol consumption.

Not a fit: Patients who do not engage in binge drinking or have no history of alcohol use disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic strategies for reducing binge drinking and its associated health risks.

How similar studies have performed: Previous research has shown promising results in understanding the neural mechanisms of alcohol consumption, suggesting that this approach could yield valuable insights.

Where this research is happening

Chicago, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.