Understanding the biology of human pain tissues
INTERCEPT: Integrated Research Center for human Pain Tissues
['FUNDING_OTHER'] · WASHINGTON UNIVERSITY · NIH-10929973
This study is looking at how chronic pain works in the body by examining the cells in human nerves, with the goal of finding better ways to manage pain and reduce the need for opioids.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-10929973 on ClinicalTrials.gov |
What this research studies
This research focuses on chronic pain, which affects millions of Americans, and aims to improve our understanding of the biological mechanisms behind pain. By analyzing human pain tissues, the project seeks to identify the various cell types involved in pain processing and how they function at a molecular level. Utilizing advanced techniques like single nuclei RNA sequencing and spatial transcriptomics, researchers will create a detailed atlas of gene expression in human peripheral nerves. This foundational knowledge could lead to better pain management strategies and alternatives to opioid treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic pain conditions who are seeking alternative treatment options.
Not a fit: Patients with acute pain or those not experiencing chronic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatments for chronic pain, reducing reliance on opioids.
How similar studies have performed: Previous research has shown promise in understanding pain mechanisms, but this project aims to provide a novel and comprehensive approach to studying human pain tissues.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GEREAU, ROBERT W — WASHINGTON UNIVERSITY
- Study coordinator: GEREAU, ROBERT W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.