Understanding the biological factors influencing dementia progression

Biomarker Core

NIH-funded research University of California at Davis · NIH-10890771

This study is looking at how different biological factors influence memory loss and dementia in older adults from various backgrounds, and by donating blood samples, participants will help researchers learn more about Alzheimer's and related conditions to create better treatments for those at risk.

Quick facts

Grant typeP30 center grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-10890771 on NIH RePORTER

What this research studies

This research focuses on identifying the complex biological factors that affect how cognitive decline and dementia progress in older adults from diverse backgrounds. By collecting and analyzing blood samples, the study aims to create a detailed understanding of Alzheimer's disease and other related conditions. Participants will contribute to a biorepository that helps researchers assess various biomarkers associated with cognitive decline. This comprehensive approach will enable the development of targeted interventions for individuals at risk of dementia.

Who could benefit from this research

Good fit: Ideal candidates for participation are older adults, particularly those from diverse ethnic and racial backgrounds, who may be experiencing cognitive decline or are at risk for dementia.

Not a fit: Patients with early-stage dementia or those who do not have any cognitive decline may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective, personalized treatments for dementia and related cognitive disorders.

How similar studies have performed: Previous research has shown promise in using biomarker assessments to understand dementia progression, indicating that this approach has potential for significant insights.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injuryAlzheimer disease dementiaAlzheimer syndromeAlzheimer's DiseaseAlzheimer's disease pathology
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.