Understanding the biological factors behind opioid addiction

Integrative Omics Center for Accelerating Neurobiological Understanding of Opioid Addiction (ICAN)

NIH-funded research Research Triangle Institute · NIH-11086850

This study is looking into the biological reasons behind opioid addiction by examining genetic and molecular information from people and animals, with the goal of helping us understand why some people are more likely to become addicted than others.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionResearch Triangle Institute NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project IDNIH-11086850 on NIH RePORTER

What this research studies

This research aims to uncover the biological drivers of opioid addiction by conducting extensive studies that integrate genetic and molecular data from both humans and animal models. The project will analyze large datasets to identify specific genes and networks that contribute to addiction, ultimately creating a national resource for further research. By combining insights from various omics technologies, the research seeks to address the complexities of opioid addiction and improve our understanding of individual differences in susceptibility to this condition.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with a history of opioid use or addiction, as well as those with genetic predispositions to addictive behaviors.

Not a fit: Patients who do not have any history of opioid use or addiction may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective prevention and treatment strategies for opioid addiction.

How similar studies have performed: Previous research has shown success in using integrated omics approaches to understand other addictive disorders, suggesting potential for similar breakthroughs in opioid addiction.

Where this research is happening

Research Triangle Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.