Understanding the best ways to add medications for treating high blood pressure.
Real-world Evidence to Inform Decisions for Hypertension Treatment Escalation
This study is looking at how to help adults with high blood pressure who aren't getting good results from just one medication by exploring the benefits and safety of adding a second medicine that fits their unique needs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10904999 on NIH RePORTER |
What this research studies
This research investigates how to improve treatment for high blood pressure in adults who are not achieving adequate control with a single medication. It aims to gather real-world evidence to determine the effectiveness and safety of adding a second antihypertensive drug based on individual patient characteristics. By analyzing variations in treatment practices, the study seeks to provide better guidance for healthcare providers on which additional medications may work best for different patients. The ultimate goal is to enhance clinical guidelines and improve patient outcomes in hypertension management.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are currently being treated for hypertension but are not achieving adequate blood pressure control with a single medication.
Not a fit: Patients who have well-controlled hypertension with their current treatment regimen may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients with high blood pressure.
How similar studies have performed: Other research has shown promise in using real-world evidence to inform treatment decisions, suggesting that this approach could yield valuable insights.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Lu, Yuan — Yale University
- Study coordinator: Lu, Yuan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.