Understanding the behavior of uncertain lung nodules over time
Characterizing longitudinal dynamics of indeterminate pulmonary nodules using semantic, radiomic, and deep features
['FUNDING_U01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11135001
This study is looking at how certain lung nodules change over time using special imaging and patient health records, to help doctors better understand if these nodules are harmless or not, which can ease worries and avoid unnecessary treatments for patients.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11135001 on ClinicalTrials.gov |
What this research studies
This research investigates how indeterminate pulmonary nodules (IPNs) behave over time using advanced imaging techniques and patient medical histories. By analyzing data from low-dose computed tomography (LDCT) scans, the study aims to improve the prediction of whether these nodules are benign or malignant. The approach includes tracking changes in the nodules and their surrounding tissues across multiple scans, which can help reduce patient anxiety and unnecessary medical interventions. The ultimate goal is to enhance early diagnosis and treatment options for patients with these nodules.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been found to have indeterminate pulmonary nodules between 6-30 mm in diameter.
Not a fit: Patients with clearly diagnosed lung conditions or those without any pulmonary nodules may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of lung nodules, reducing anxiety and unnecessary procedures for patients.
How similar studies have performed: Previous studies have shown promise in using imaging biomarkers for lung cancer detection, indicating that this approach has potential for success.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WONG, DAVID T — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: WONG, DAVID T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.