Understanding the bacteria around the eyes
Official title: Determinants of the periocular microbiome
Funded at University of Washington · NIH-10868496 · Data updated 2026-11-12
This study is looking at the tiny germs on the eyelid margin to see how they might affect eye problems like blepharitis and dry eye, and it's for people who want to understand more about their eye health by participating in a fun twin study with some simple tests and questionnaires.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $804,244 |
| NIH project number | 5U24EY035062-02 |
| Project ID | NIH-10868496 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals aged 21 and older with conditions like blepharitis or dry eye syndrome.
✕Less likely to help
Patients with no history of eye conditions or those under 21 years old may not benefit from this research.
What this research studies
This research investigates the microbiome of the eyelid margin, which may play a role in various eye diseases such as blepharitis and dry eye syndrome. By studying a large group of twins, researchers will collect data through questionnaires, ocular examinations, and swabs from the eyelid area. The collected samples will undergo advanced genetic sequencing to analyze the microbial composition and its potential genetic influences. This approach aims to uncover the variability in the eyelid microbiome and its implications for eye health.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for common eye conditions.
How similar studies have gone: Previous research has shown promising results in understanding the microbiome's role in health, suggesting potential for success in this area.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Van Gelder, Russell N. — University of Washington
- Study coordinator: Van Gelder, Russell N.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.