Understanding the 3D structures of proteins in infectious diseases.
Centers for Research on Structural Biology of Infectious Diseases for Anti-Microbial Resistant Research
This study is looking at the tiny structures of proteins from germs that cause infections, especially those that are hard to treat, to help find new ways to fight these tough bacteria and keep you healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Seattle Children's Hospital NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11160406 on NIH RePORTER |
What this research studies
This research focuses on using advanced structural biology techniques to determine the three-dimensional atomic structures of proteins from various infectious disease-causing organisms. By identifying these structures, researchers aim to understand how these proteins function at a molecular level, which can lead to the development of new treatments for infections caused by antibiotic-resistant bacteria. The project targets proteins from pathogens that are prioritized by health authorities due to their impact on public health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from infections caused by antibiotic-resistant bacteria or those at high risk for such infections.
Not a fit: Patients with infections that are not caused by the targeted antibiotic-resistant bacteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new therapies to combat antibiotic-resistant infections.
How similar studies have performed: Previous research has shown success in using structural biology to inform drug development against infectious diseases, indicating a promising approach.
Where this research is happening
Seattle, United States
- Seattle Children's Hospital — Seattle, United States (Active)
Researchers
- Principal investigator: Myler, Peter — Seattle Children's Hospital
- Study coordinator: Myler, Peter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.