Understanding THC's Immediate Effects in Older Adults

Acute effects of THC in older adults

NIH-funded research Yale University · NIH-11142596

This project looks at how THC, a component of cannabis, immediately affects the mind and body of healthy older adults.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11142596 on NIH RePORTER

What this research studies

As cannabis use becomes more common among older adults, we need to understand how it affects them differently than younger people. This project explores how THC might impact thinking, anxiety, and heart health in older individuals, considering natural changes that come with aging. We want to see if older adults might be more sensitive to THC's effects due to differences in their brain and body systems. The goal is to gather important information to help older adults make informed decisions about cannabis use.

Who could benefit from this research

Good fit: Ideal candidates would be healthy older adults interested in understanding the immediate effects of THC.

Not a fit: Patients who are not older adults or who have significant health conditions that would prevent safe participation may not receive direct benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could provide crucial safety information and guidance for older adults considering or currently using cannabis.

How similar studies have performed: There is very limited high-quality information on the acute effects of cannabinoids specifically in healthy older adults, making this a novel area of investigation.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.