Understanding temperature regulation in people with a leg amputation to prevent tissue complications
Thermoregulation in individuals with a leg amputation: mechanics and vascular physiology factors to understand risks for tissue complications
This study looks at how temperature changes in the legs of people with a leg amputation can affect their skin health, especially for those with diabetes, to help find better ways to prevent issues like pressure sores.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-10886611 on NIH RePORTER |
What this research studies
This research investigates how temperature regulation affects individuals with a leg amputation, focusing on the intact leg and residual limb. It aims to understand the mechanical and vascular factors that contribute to skin temperature changes, which can lead to complications like pressure sores. By studying how these factors interact, especially in patients with diabetes, the research seeks to identify risks and improve early diagnosis and intervention strategies. The methodology includes monitoring temperature responses during walking and analyzing the impact of mechanical forces on tissue health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 21 and older who have undergone a unilateral leg amputation, particularly those with diabetes.
Not a fit: Patients who have not experienced a leg amputation or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies for tissue complications in amputees, enhancing their quality of life.
How similar studies have performed: Previous studies have shown promising results in understanding temperature regulation in similar populations, indicating that this approach may yield valuable insights.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Takahashi, Kota — University of Utah
- Study coordinator: Takahashi, Kota
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.