Understanding T cells' role in pregnancy and preterm birth
Function of T cells at the Maternal-Fetal Interface
This study is looking at how certain immune cells in the placenta might affect the risk of preterm birth, aiming to understand what happens during pregnancy that could lead to complications for both moms and babies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11000807 on NIH RePORTER |
What this research studies
This research investigates how T cells function at the maternal-fetal interface, particularly in relation to preterm birth (PTB). By examining the immune response within the placenta, the study aims to uncover the mechanisms that lead to complications during pregnancy. The researchers will utilize advanced techniques to analyze immune cell behavior and inflammation in placental tissues, which could provide insights into the causes of PTB. This work is crucial as it addresses a significant health issue affecting infants and mothers.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant individuals at risk of preterm birth or those who have experienced complications during pregnancy.
Not a fit: Patients who are not pregnant or those with full-term pregnancies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing preterm birth and enhancing maternal and infant health.
How similar studies have performed: Previous research has shown promising results in understanding immune responses in pregnancy, suggesting that this approach could yield valuable insights.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Konnikova, Liza — Yale University
- Study coordinator: Konnikova, Liza
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.