Understanding T Cells and IL-9 in Preterm Labor and Birth
T Cells and IL-9 Signaling at the Maternal-Fetal Interface in Preterm Labor and Birth
['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-11171672
This project explores how certain immune cells and a molecule called IL-9 contribute to preterm labor and birth, and how vitamin D might help prevent it.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11171672 on ClinicalTrials.gov |
What this research studies
Preterm birth, often without clear infection, is a major concern for many families. This project looks at how specific immune cells, called T cells, and a signaling molecule, IL-9, in the womb might lead to early labor. Researchers are working to understand how IL-9 causes preterm birth and affects babies, and how vitamin D could potentially stop this process. They also aim to find new types of T cells involved in human preterm labor, which could open doors for new treatments.
Who could benefit from this research
Good fit: This foundational research is for pregnant individuals at risk for preterm labor, or those who have experienced it, who might contribute to future studies.
Not a fit: Patients not experiencing or at risk for preterm labor would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to prevent preterm birth and improve health outcomes for babies.
How similar studies have performed: This project builds on existing published and preliminary data suggesting a role for T cells and IL-9 in preterm labor, indicating some prior foundational success in this area.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOMEZ-LOPEZ, NARDHY — WASHINGTON UNIVERSITY
- Study coordinator: GOMEZ-LOPEZ, NARDHY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.