Understanding T-cell Response in Colorectal Cancer

Interdisciplinary Epidemiologic Consortium to Investigate T-cell Response in Colorectal Cancer

['FUNDING_R01'] · FRED HUTCHINSON CANCER CENTER · NIH-11066501

This project explores how the body's immune cells, called T-cells, respond to colorectal cancer and what factors influence this response.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorFRED HUTCHINSON CANCER CENTER (nih funded)
Locations1 site (SEATTLE, UNITED STATES)
Trial IDNIH-11066501 on ClinicalTrials.gov

What this research studies

Our immune system plays a big role in how cancers grow and progress, especially in colorectal cancer. We know that a strong T-cell response often leads to better outcomes for patients. This project aims to discover what personal factors, like genetics and lifestyle choices, and what tumor characteristics, such as specific bacteria or gene changes, are connected to this important T-cell response. By understanding these connections, we hope to find new ways to improve treatments for colorectal cancer.

Who could benefit from this research

Good fit: This research focuses on understanding factors in patients with colorectal cancer.

Not a fit: Patients without colorectal cancer would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to new ways to predict how patients with colorectal cancer will respond to treatment and help develop more effective immunotherapies.

How similar studies have performed: While the importance of T-cell response in cancer is known, this project aims to uncover new specific genetic, lifestyle, and tumor factors influencing it, making its approach novel in its comprehensive scope.

Where this research is happening

SEATTLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.