Understanding swallowing difficulties and their treatment
Evolution of the Chicago Classification: Bridging Physiology and Mechanics
['FUNDING_R01'] · NORTHWESTERN UNIVERSITY AT CHICAGO · NIH-10979070
This study is looking into why some people have trouble swallowing and experience heartburn, focusing on how the esophagus works when we eat, to help doctors find better ways to diagnose and treat these issues for patients like you.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTHWESTERN UNIVERSITY AT CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-10979070 on ClinicalTrials.gov |
What this research studies
This research investigates the causes of swallowing difficulties, known as dysphagia, and gastroesophageal reflux disease (GERD), focusing on the biomechanics of the esophagus rather than just muscle activity. By developing new models that assess how the esophagus responds to food and pressure, the research aims to improve diagnosis and treatment options for patients suffering from these conditions. The study will utilize advanced techniques to measure esophageal function and develop predictive models to better understand symptoms and treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing swallowing difficulties or gastroesophageal reflux disease.
Not a fit: Patients with non-esophageal related swallowing issues or those without dysphagia or GERD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for swallowing difficulties and related disorders, improving patients' quality of life.
How similar studies have performed: Previous research has shown promise in understanding esophageal function and treatment approaches, but this study aims to explore novel methodologies that have not been extensively tested.
Where this research is happening
CHICAGO, UNITED STATES
- NORTHWESTERN UNIVERSITY AT CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PANDOLFINO, JOHN E — NORTHWESTERN UNIVERSITY AT CHICAGO
- Study coordinator: PANDOLFINO, JOHN E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.