Understanding Stroke Risk in Diabetes with Low Blood Sugar
Cerebral ischemia and exposure to recurrent hypoglycemia in diabetes
This project explores how repeated episodes of low blood sugar in people with diabetes might increase their risk and worsen the effects of stroke.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11127425 on NIH RePORTER |
What this research studies
We know that diabetes increases the risk and severity of stroke, and intensive treatments for diabetes can sometimes lead to low blood sugar. This work looks at how these low blood sugar episodes might make blood clots more likely to form and cause more damage during a stroke. By understanding these connections, we hope to find ways to protect the brain health of people living with diabetes. Our goal is to uncover the specific ways low blood sugar affects the body to make stroke worse.
Who could benefit from this research
Good fit: This foundational research is relevant to patients with type 1 or type 2 diabetes who experience recurrent low blood sugar episodes and are at risk for stroke.
Not a fit: Patients without diabetes or those who do not experience recurrent hypoglycemia would likely not directly benefit from this specific line of research.
Why it matters
Potential benefit: If successful, this work could lead to new strategies to reduce stroke severity and incidence for patients with diabetes, improving their long-term brain health.
How similar studies have performed: Epidemiological and clinical studies have highlighted the link between diabetes, intensive therapy, hypoglycemia, and stroke, but the specific mechanisms explored here are being further clarified.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Dave, Kunjan R — University of Miami School of Medicine
- Study coordinator: Dave, Kunjan R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.