Understanding stress responses in takotsubo syndrome

Heterogeneity and predictors of stress reactivity in takotsubo syndrome

['FUNDING_R01'] · MIRIAM HOSPITAL · NIH-10766788

This study is looking at takotsubo syndrome, a temporary heart condition that often affects older women, to find out what triggers it, like stress, and how these triggers impact heart health and stress responses.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMIRIAM HOSPITAL (nih funded)
Locations1 site (PROVIDENCE, UNITED STATES)
Trial IDNIH-10766788 on ClinicalTrials.gov

What this research studies

This research investigates takotsubo syndrome, a condition that causes temporary heart failure, particularly in older women. It aims to identify the different triggers that can lead to this syndrome, which may include emotional and physical stressors. By examining how these triggers affect the sympathetic nervous system and heart function, the study seeks to fill important knowledge gaps about the condition. Patients will be monitored for their heart health and stress responses to better understand the syndrome's variability.

Who could benefit from this research

Good fit: Ideal candidates for this research are older women who have experienced takotsubo syndrome or are at risk for it.

Not a fit: Patients who do not have takotsubo syndrome or are not at risk for heart-related issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for patients with takotsubo syndrome.

How similar studies have performed: While there has been some research on takotsubo syndrome, this study aims to explore novel aspects of its triggers and responses, making it a potentially groundbreaking investigation.

Where this research is happening

PROVIDENCE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.