Understanding stress responses in female adolescents with a family history of depression.
Tracking the dynamic trajectory of behavioral, physiological, and neurobiological stress responses in female adolescents at high and low familial risk for depression.
This study is looking at how stress impacts teenage girls, especially those with a family history of depression, to better understand how their brains and bodies react during this important time in their lives.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mclean Hospital NIH-funded |
| Lab location | 1 site (Belmont, United States) |
| Project ID | NIH-11131372 on NIH RePORTER |
What this research studies
This research investigates how stress affects female adolescents, particularly those with a family history of Major Depressive Disorder (MDD). It focuses on understanding the brain and body responses to stress during early adolescence, a critical time for the onset of depression. By examining the interactions between brain networks and physiological responses, the study aims to identify patterns that may predict future depression. Participants will undergo assessments to track their behavioral and biological reactions to stress over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are female adolescents aged 12 to 20 with a family history of Major Depressive Disorder.
Not a fit: Patients who do not have a familial history of depression or are outside the age range of 12 to 20 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to early identification and intervention strategies for adolescents at risk of developing depression.
How similar studies have performed: Previous research has shown promising results in understanding stress responses and their link to depression, making this approach both relevant and potentially impactful.
Where this research is happening
Belmont, United States
- Mclean Hospital — Belmont, United States (Active)
Researchers
- Principal investigator: Belleau, Emily — Mclean Hospital
- Study coordinator: Belleau, Emily
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.