Understanding spinal cord systems for recovery after injury
A new mechanistic and technological framework for uncovering the spinal cord neural systems important for functional recovery after injury
This study is looking at how certain nerve cells in the spinal cord help mice recover their movement after an injury, which could lead to better ways to help people get back on their feet after similar injuries.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers, the State Univ of N.j. NIH-funded |
| Lab location | 1 site (Piscataway, United States) |
| Project ID | NIH-10930143 on NIH RePORTER |
What this research studies
This research investigates the neural systems in the spinal cord that are crucial for recovery following spinal cord injuries. By using advanced genetic techniques in mice and tracking their motor movements, the team aims to identify specific neurons that play a role in motor recovery. The focus is on understanding how sensory information influences movement and behavior, particularly through a type of neuron known as parvalbumin positive interneurons. This could lead to better rehabilitation strategies that enhance recovery after injury.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced spinal cord injuries and are seeking innovative rehabilitation options.
Not a fit: Patients with non-spinal cord related injuries or conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved rehabilitation techniques that enhance motor recovery for individuals with spinal cord injuries.
How similar studies have performed: Previous research has shown promise in understanding spinal cord recovery mechanisms, but this approach is innovative in its specific focus on intermediate zone neurons.
Where this research is happening
Piscataway, United States
- Rutgers, the State Univ of N.j. — Piscataway, United States (Active)
Researchers
- Principal investigator: Abraira, Victoria Eugenia Guadalupe — Rutgers, the State Univ of N.j.
- Study coordinator: Abraira, Victoria Eugenia Guadalupe
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.