Understanding Speech Difficulties in Aphasia After Stroke
Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia
This research aims to better understand how the brain produces sentences and why this process becomes difficult for people with aphasia after a stroke, hoping to improve future treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Maryland, College Park NIH-funded |
| Lab location | 1 site (College Park, United States) |
| Project ID | NIH-11178568 on NIH RePORTER |
What this research studies
Many people who have a stroke experience a condition called agrammatic aphasia, which makes it hard to form complete sentences, use correct grammar, and speak at a normal pace. Current approaches to helping with these speech difficulties often focus on just one symptom at a time, leading to limited improvements in daily communication. This project seeks to understand how different brain processes—like word choice, grammar, and muscle movements for speech—work together to create sentences, and how these processes break down in agrammatic aphasia. By exploring the brain's activity over time, we hope to uncover the root causes of these speech challenges. This deeper understanding could lead to more effective and comprehensive therapies for people living with aphasia.
Who could benefit from this research
Good fit: This research is most relevant to individuals who have experienced a stroke and developed agrammatic aphasia, characterized by difficulties in sentence production and grammar.
Not a fit: Patients with other forms of aphasia not primarily characterized by agrammatism, or those without a history of stroke, may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this research could lead to new and more effective therapies that significantly improve communication abilities for individuals with post-stroke agrammatic aphasia.
How similar studies have performed: While current interventions for agrammatic aphasia have shown some success, this project proposes a novel, more integrated approach to understanding the underlying brain mechanisms, moving beyond single-symptom focuses.
Where this research is happening
College Park, United States
- Univ of Maryland, College Park — College Park, United States (Active)
Researchers
- Principal investigator: Faroqi Shah, Yasmeen — Univ of Maryland, College Park
- Study coordinator: Faroqi Shah, Yasmeen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.