Understanding speech and swallowing challenges in individuals with Down syndrome

A Physiologically Integrated Approach to Studying Mechanisms of Speech Production and Swallow Function in Down Syndrome

['FUNDING_R01'] · PENNSYLVANIA STATE UNIVERSITY, THE · NIH-10657309

This study is looking at the speech and swallowing challenges that people with Down syndrome face, so we can find better ways to help them stay healthy and safe.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorPENNSYLVANIA STATE UNIVERSITY, THE (nih funded)
Locations1 site (UNIVERSITY PARK, UNITED STATES)
Trial IDNIH-10657309 on ClinicalTrials.gov

What this research studies

This research investigates the unique challenges faced by individuals with Down syndrome regarding speech production and swallowing functions. It aims to explore the physiological and neurological factors that contribute to these difficulties, which can lead to serious health risks such as aspiration pneumonia. By examining the specific oral and cognitive characteristics of individuals with Down syndrome, the study seeks to develop tailored interventions that are more effective than current methods borrowed from other populations. The research will involve a combination of clinical assessments and innovative methodologies to better understand these mechanisms.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with Down syndrome, particularly those experiencing difficulties with speech and swallowing.

Not a fit: Patients without Down syndrome or those who do not experience speech or swallowing difficulties may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved speech and swallowing interventions specifically designed for individuals with Down syndrome, enhancing their quality of life.

How similar studies have performed: While there has been research on speech and swallowing in other populations, this approach is novel as it specifically addresses the unique needs of individuals with Down syndrome.

Where this research is happening

UNIVERSITY PARK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.