Understanding specific brain cell types affected by aging and Alzheimer's disease
Circuit-specific cell types in aging and Alzheimer's disease
This study is looking at certain brain cells that may be affected by aging and Alzheimer's disease to help us understand how these changes impact brain function, which could lead to better ways to support people dealing with Alzheimer's and memory issues as they get older.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Salk Institute for Biological Studies NIH-funded |
| Lab location | 1 site (La Jolla, UNITED STATES) |
| Project ID | NIH-11124719 on NIH RePORTER |
What this research studies
This research aims to identify and define specific types of brain cells that are vulnerable to changes during aging and Alzheimer's disease. By examining the connections and molecular changes in these cells, the study seeks to understand how aging and Alzheimer's impact brain function. The approach combines advanced techniques to analyze individual neurons and their connectivity, providing insights into the progression of these conditions. This knowledge could lead to better understanding and potential interventions for those affected by Alzheimer's and age-related cognitive decline.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing cognitive decline or those at risk for Alzheimer's disease.
Not a fit: Patients with early-stage Alzheimer's or those without cognitive impairment may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating Alzheimer's disease and improving cognitive health in aging populations.
How similar studies have performed: Previous research has shown promise in understanding brain cell changes in Alzheimer's, making this approach a continuation of successful methodologies.
Where this research is happening
La Jolla, UNITED STATES
- Salk Institute for Biological Studies — La Jolla, United States (Active)
Researchers
- Principal investigator: Lee, Kuo-Fen — Salk Institute for Biological Studies
- Study coordinator: Lee, Kuo-Fen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.