Understanding sound sensitivity in autism using a rat model
Mechanisms of sound hypersensitivity in a rat model of autism
['FUNDING_CAREER'] · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · NIH-10821474
This study is looking at how some people with autism, especially those with Fragile X Syndrome, experience sounds more intensely than others, and it aims to understand how their brains process these sounds to help improve their everyday lives.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (nih funded) |
| Locations | 1 site (CHAMPAIGN, UNITED STATES) |
| Trial ID | NIH-10821474 on ClinicalTrials.gov |
What this research studies
This research investigates how auditory hypersensitivity, a common issue in autism spectrum disorders (ASD), affects sound perception. By using a rat model of Fragile X Syndrome, which is linked to ASD, the study aims to identify the underlying brain mechanisms that lead to exaggerated sound perception and avoidance behaviors. Researchers will employ innovative behavioral tests and advanced electrophysiological techniques to analyze how changes in auditory brain networks contribute to these sensory challenges. The findings could provide valuable insights into the fundamental brain alterations associated with autism.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with autism spectrum disorders, particularly those experiencing significant auditory hypersensitivity.
Not a fit: Patients without autism spectrum disorders or those not experiencing sound sensitivity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals with auditory hypersensitivity in autism.
How similar studies have performed: Previous research has shown promising results in understanding sensory processing in autism, suggesting that this approach could yield valuable insights.
Where this research is happening
CHAMPAIGN, UNITED STATES
- UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN — CHAMPAIGN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: AUERBACH, BENJAMIN D — UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
- Study coordinator: AUERBACH, BENJAMIN D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Communication Disorders