Understanding sound perception issues in children with Fragile X Syndrome
Tracking early emergence of sound perception impairments in FXS with multimodal fNIRS/EEG
This study is looking at how children with Fragile X Syndrome hear and process sounds, using special tools to see how their brains respond, so we can better understand their speech and language challenges and help them earlier.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-10909067 on NIH RePORTER |
What this research studies
This research focuses on identifying how sensory processing issues, particularly related to sound perception, develop in children with Fragile X Syndrome (FXS). Using advanced techniques like functional near-infrared spectroscopy (fNIRS) and electroencephalography (EEG), the study aims to measure brain activity and auditory responses in young children. The goal is to uncover the connections between sensory anomalies and challenges in speech and language development, ultimately improving early diagnosis and intervention strategies for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children diagnosed with Fragile X Syndrome, particularly those under the age of 10.
Not a fit: Patients without a diagnosis of Fragile X Syndrome or those over the age of 10 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and earlier identification of sound perception impairments in children with FXS, enhancing treatment options.
How similar studies have performed: Previous research has shown promise in using neurophysiological methods to study sensory processing in neurodevelopmental disorders, indicating that this approach could yield valuable insights.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Smith, Elizabeth Gayle — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Smith, Elizabeth Gayle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.