Understanding social cognitive challenges in older adults with schizophrenia
Official title: Progression of Social Cognitive Deficits in Mid- and Late-Life Schizophrenia Spectrum Disorders
Funded at Ohio State University · NIH-11001581 · Data updated 2026-11-12
This study is looking at how social thinking skills change as people with schizophrenia get older, and it includes both those with the condition and healthy individuals to better understand these changes and find ways to help improve social interactions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | December 15, 2023 |
| Project end | October 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $752,698 |
| NIH project number | 5R01MH135117-02 |
| Project ID | NIH-11001581 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 35 to 75 with schizophrenia spectrum disorders, as well as younger individuals with early psychosis and age-matched healthy participants.
✕Less likely to help
Patients outside the age range of 18 to 75 or those without schizophrenia spectrum disorders may not benefit from this research.
What this research studies
This research investigates how social cognitive deficits evolve in individuals with schizophrenia spectrum disorders as they age, particularly focusing on those in mid- to late-life. By recruiting a diverse group of participants, including those with schizophrenia and healthy individuals, the study aims to assess various cognitive and psychiatric factors. Participants will undergo detailed evaluations, including EEG assessments, to explore the neural mechanisms behind these cognitive challenges. The goal is to identify effective interventions tailored to improve social functioning in this population.
Why it matters
Potential benefit: If successful, this research could lead to targeted treatments that enhance social functioning and quality of life for older adults with schizophrenia spectrum disorders.
How similar studies have gone: Previous research has shown promising results in understanding cognitive deficits in schizophrenia, but this specific focus on mid- to late-life social cognition is relatively novel.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Tso, Ivy Fei — Ohio State University
- Study coordinator: Tso, Ivy Fei
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.