Understanding social cognitive challenges in older adults with schizophrenia

Progression of Social Cognitive Deficits in Mid- and Late-Life Schizophrenia Spectrum Disorders

['FUNDING_R01'] · OHIO STATE UNIVERSITY · NIH-11001581

This study is looking at how social thinking skills change as people with schizophrenia get older, and it includes both those with the condition and healthy individuals to better understand these changes and find ways to help improve social interactions.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorOHIO STATE UNIVERSITY (nih funded)
Locations1 site (Columbus, UNITED STATES)
Trial IDNIH-11001581 on ClinicalTrials.gov

What this research studies

This research investigates how social cognitive deficits evolve in individuals with schizophrenia spectrum disorders as they age, particularly focusing on those in mid- to late-life. By recruiting a diverse group of participants, including those with schizophrenia and healthy individuals, the study aims to assess various cognitive and psychiatric factors. Participants will undergo detailed evaluations, including EEG assessments, to explore the neural mechanisms behind these cognitive challenges. The goal is to identify effective interventions tailored to improve social functioning in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 35 to 75 with schizophrenia spectrum disorders, as well as younger individuals with early psychosis and age-matched healthy participants.

Not a fit: Patients outside the age range of 18 to 75 or those without schizophrenia spectrum disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to targeted treatments that enhance social functioning and quality of life for older adults with schizophrenia spectrum disorders.

How similar studies have performed: Previous research has shown promising results in understanding cognitive deficits in schizophrenia, but this specific focus on mid- to late-life social cognition is relatively novel.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.