Understanding smell loss in older adults
Olfactory Dysfunction in Aging Adults
This study is looking at why many older adults have trouble smelling and how it can affect their health, with the hope of finding better ways to help those who are struggling with this issue.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical University of South Carolina NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project ID | NIH-10890067 on NIH RePORTER |
What this research studies
This research investigates the common issue of olfactory dysfunction, or loss of smell, in older adults, which affects over 50% of this population and is linked to increased mortality. The study aims to identify specific anatomical sites along the olfactory pathway that contribute to this dysfunction and to classify patients based on these sites and their underlying mechanisms. By utilizing advanced diagnostic protocols and olfactory-specific biomarkers, the research seeks to develop personalized treatment options for those affected. The ultimate goal is to enhance the understanding and management of olfactory dysfunction in aging individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing olfactory dysfunction or loss of smell.
Not a fit: Patients who do not have olfactory dysfunction or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods and targeted treatments for older adults experiencing smell loss.
How similar studies have performed: Previous research has highlighted the prevalence of olfactory dysfunction in older adults, but this approach aims to provide a novel classification system that has not been extensively tested.
Where this research is happening
Charleston, United States
- Medical University of South Carolina — Charleston, United States (Active)
Researchers
- Principal investigator: Schlosser, Rodney Jon — Medical University of South Carolina
- Study coordinator: Schlosser, Rodney Jon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.