Understanding Small Cell Lung Cancer to Discover New Treatments
Investigating molecular and cellular mechanisms of SCLC development to identify novel therapeutic strategies
This research aims to understand how small cell lung cancer develops and resists treatment, hoping to find new ways to fight this aggressive disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11159419 on NIH RePORTER |
What this research studies
Our laboratory is deeply interested in how cancer cells change and adapt, especially in small cell lung cancer (SCLC), which is a very deadly form of lung cancer. We are looking closely at a specific protein called Rb, which plays a role in how cancer cells behave and why they sometimes don't respond to current therapies. By using special tools and models, we hope to uncover new insights into SCLC progression and maintenance that are difficult to find with traditional methods. This deeper understanding is crucial for developing much-needed new treatment options for patients.
Who could benefit from this research
Good fit: This foundational research is for patients with small cell lung cancer, as it seeks to understand the disease at a basic level to inform future therapies.
Not a fit: Patients without small cell lung cancer would not directly benefit from this specific research, as it is focused solely on this particular cancer type.
Why it matters
Potential benefit: If successful, this work could lead to the discovery of entirely new treatment approaches for small cell lung cancer, offering hope where current options are limited.
How similar studies have performed: Our laboratory has made significant contributions to this field, with pioneering work on Rb-mutant small cell lung cancer providing fundamental new insights.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Sage, Julien — Stanford University
- Study coordinator: Sage, Julien
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.