NIH-funded research NIH-funded research

Understanding sleep patterns in adolescents with abdominal pain disorders

Official title: Disrupted sleep architecture in adolescents with functional abdominal pain disorders

Funded at Cincinnati Childrens Hosp Med Ctr · NIH-11013333 · Data updated 2026-11-12

This study is looking at how sleep patterns impact teenagers with tummy pain and whether a special treatment called PENFS can help them sleep better and feel less pain.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCincinnati Childrens Hosp Med Ctr
NIH-funded
Lab location1 site (Cincinnati, United States)
Project startApril 1, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$191,007
NIH project number5K23DK135797-03
Project IDNIH-11013333 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents diagnosed with functional abdominal pain disorders who experience sleep disturbances.

Less likely to help

Patients without functional abdominal pain disorders or those who do not experience sleep issues may not benefit from this research.

What this research studies

This research investigates how sleep architecture affects adolescents suffering from functional abdominal pain disorders (FAPD). It aims to understand the relationship between sleep quality and gastrointestinal symptoms by using advanced sleep monitoring techniques. The study will also evaluate the effects of a specific therapy, Percutaneous Electrical Nerve Field Stimulation (PENFS), on sleep patterns and pain relief. By comparing sleep data before and after treatment, the research seeks to uncover important insights that could improve patient care.

Why it matters

Potential benefit: If successful, this research could lead to better treatment strategies for adolescents with abdominal pain by addressing sleep disturbances.

How similar studies have gone: While there is preliminary data suggesting the importance of sleep in FAPD, this specific approach to objectively measure sleep architecture in relation to treatment outcomes is novel.

Where this research is happening

  • Cincinnati Childrens Hosp Med Ctr
    Cincinnati, United States
    Active

Researchers

  • Principal investigator: Santucci, Neha Richard — Cincinnati Childrens Hosp Med Ctr
  • Study coordinator: Santucci, Neha Richard

Related research

Other NIH-funded projects on the same topics.

  • Improving ultrasound use for diagnosing abdominal pain in rural children

    This project tests ways to bring affordable, radiation-free ultrasound to kids with belly pain in rural areas.

    NIH research Research Inst Nationwide Children's Hosp · Columbus, United States · NIH-11374059

  • Circadian rhythms and abdominal pain in teens

    Teens with functional abdominal pain may have a body clock timing issue, and this study looks at how circadian phase relates to their pain and daily functioning.

    NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11353719

  • Online parent program to help prevent tummy pain in young children

    An internet-based program for parents with IBS that teaches ways to lower their 4–6 year-old children's risk of developing tummy pain and related worry.

    NIH research Seattle Children's Hospital · Seattle, United States · NIH-11314594

  • Internet-based intervention to help young children at risk for abdominal pain

    This study is testing a helpful online program for parents with Irritable Bowel Syndrome (IBS) to see if it can reduce tummy aches in their young kids aged 4-6 by teaching parents ways to manage stress and model healthier habits.

    NIH research Seattle Children's Hospital · Seattle, United States · NIH-11082248

  • Home-based electrical stimulation for abdominal pain relief

    This study is testing a gentle, needle-free method called transcutaneous electrical acustimulation (TEA) to help people with irritable bowel syndrome (IBS) manage their abdominal pain more easily at home or work, and it will also include a handy app to help track treatment progress.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10916399

  • Improving decision-making for children with abdominal pain in emergency departments

    This study is looking at how to better diagnose and treat kids with tummy pain in emergency rooms by involving both doctors and families in the decision-making process, with the hope of reducing unnecessary tests and keeping kids safe.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10894055

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.