Understanding sleep apnea after a stroke
Official title: Towards personalized medicine: pathophysiologic contributions to post-stroke sleep apnea
Funded at University of Michigan at Ann Arbor · NIH-11038006 · Data updated 2026-11-12
This study is looking at how sleep apnea affects people who have had a stroke, especially focusing on Mexican American patients, to find better ways to treat their sleep problems and improve their recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | April 10, 2023 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $1,636,792 |
| NIH project number | 5R01HL164755-03 |
| Project ID | NIH-11038006 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who have experienced a stroke and may be suffering from obstructive sleep apnea.
✕Less likely to help
Patients who have not had a stroke or do not have obstructive sleep apnea may not benefit from this research.
What this research studies
This research investigates how obstructive sleep apnea (OSA) affects individuals who have experienced a stroke, particularly focusing on the unique mechanisms that contribute to this condition in stroke patients. By analyzing polysomnography (PSG) data, the study aims to categorize different types of OSA based on their underlying causes, which can vary significantly from the general population. The goal is to develop personalized treatment approaches that address these specific causes, ultimately improving outcomes for stroke survivors. The research particularly emphasizes the higher prevalence of OSA among Mexican American stroke patients, aiming to reduce health disparities in this population.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for sleep apnea in stroke survivors, improving their overall health and recovery.
How similar studies have gone: Previous research has shown promising results in understanding and treating sleep apnea through personalized approaches, suggesting that this study's focus on post-stroke patients is both relevant and potentially impactful.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Brown, Devin L — University of Michigan at Ann Arbor
- Study coordinator: Brown, Devin L
Related research
Other NIH-funded projects on the same topics.
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Personalized care for sleep apnea after stroke
Uses advanced sleep testing to find the causes of sleep apnea in adults who have had a stroke so treatments can be better matched to each person.
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Improving sleep apnea treatment for stroke patients
This study is looking at ways to better diagnose and treat sleep apnea in veterans who have had a stroke or a mini-stroke, with the hope of helping them recover and avoid more strokes in the future.
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Stroke prevention with hydroxyurea for children with sickle cell anemia in Nigeria
A multinational, patient-facing study tests whether hydroxyurea can safely prevent first strokes in Nigerian children with sickle cell anemia.
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Music-powered tools to boost blood pressure and stroke prevention for Nigerian youth and their older caregivers
This project uses popular music to help Nigerian youths and their older family members start and stick to blood pressure and stroke prevention habits.
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Determinants of Post-Stroke Cognitive Outcomes and Vascular Effects on Recovery
A large, multi-site effort aims to understand why some stroke survivors develop long-term cognitive problems and dementia, and how vascular health and pre-existing brain changes influence recovery.
-
LRP1 controls NSC movement and stroke recovery
This NIH grant studies how a brain receptor called LRP1 helps neural stem cells move to stroke injuries and support recovery in adults.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.