Understanding Skin Growth and Repair
Regulation of Epidermal Development and Differentiation-Renewal
This research aims to understand how skin cells grow and repair themselves, and what happens when these processes lead to skin inflammation or cancers like basal cell carcinoma.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rockefeller University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11086857 on NIH RePORTER |
What this research studies
Our skin constantly renews itself, and this project explores the intricate ways skin stem cells manage this process, adapting to different needs like healing wounds. We are learning how these stem cells receive signals from their surroundings to perform their specific jobs and survive stressful conditions. By understanding how these natural repair mechanisms work, we can better see what goes wrong when skin conditions like inflammation or cancers develop. This knowledge could help us find new ways to support healthy skin and address diseases.
Who could benefit from this research
Good fit: This foundational research is not directly recruiting patients but aims to benefit individuals affected by skin inflammation, skin cancers, or those needing improved wound healing.
Not a fit: Patients seeking immediate clinical interventions or direct treatment for their conditions may not find direct benefit from this basic science research at this stage.
Why it matters
Potential benefit: If successful, this work could lead to new treatments for skin inflammation and cancers by targeting the fundamental processes of skin cell growth and repair.
How similar studies have performed: This project builds upon decades of successful research by the same team, indicating a strong foundation and established expertise in this area.
Where this research is happening
New York, United States
- Rockefeller University — New York, United States (Active)
Researchers
- Principal investigator: Fuchs, Elaine — Rockefeller University
- Study coordinator: Fuchs, Elaine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.