Understanding skin cancer risks in organ transplant recipients
Identifying clinical and genetic factors for risk of multiple skin cancers in organ transplant recipients
This study is looking at why people who have had organ transplants are more likely to get skin cancer, focusing on how the medications they take to prevent their bodies from rejecting the transplant might affect their skin, with the goal of finding better ways to keep them healthy and prevent skin cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10811623 on NIH RePORTER |
What this research studies
This research investigates the clinical and genetic factors that contribute to the increased risk of developing multiple skin cancers in organ transplant recipients. It focuses on understanding how immunosuppressive medications, which are necessary for transplant success, may affect DNA repair mechanisms and influence skin cancer development. By studying a population with a high incidence of skin cancers, the research aims to identify specific risk factors and mechanisms that lead to multiple skin cancers, ultimately improving patient care and prevention strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are organ transplant recipients who are at a higher risk of developing skin cancers.
Not a fit: Patients who have not undergone organ transplantation or those without a history of skin cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better screening and prevention strategies for skin cancer in organ transplant recipients.
How similar studies have performed: Previous research has shown that studying high-risk populations can yield valuable insights into cancer mechanisms, suggesting that this approach may be effective.
Where this research is happening
Nashville, United States
- Veterans Health Administration — Nashville, United States (Active)
Researchers
- Principal investigator: Wheless, Lee E — Veterans Health Administration
- Study coordinator: Wheless, Lee E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.