Understanding Sinus Problems in Young Children with Cystic Fibrosis
Sinus Disease in Young Children with Cystic Fibrosis
This research looks at how cystic fibrosis affects sinus health and sense of smell in young children, and how a new treatment might help.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11138771 on NIH RePORTER |
What this research studies
Cystic fibrosis often causes chronic sinus problems and can affect a child's sense of smell, which can impact their daily life and overall health. While a highly effective treatment called HEMT has shown promise for adults with CF, it hasn't fully resolved sinus issues or restored smell. This project aims to understand how these problems develop in very young children with CF and to see if starting HEMT early can lead to better outcomes for their sinuses and sense of smell. We hope to learn if early treatment can prevent or significantly reduce these long-term complications.
Who could benefit from this research
Good fit: Ideal candidates for this research would be young children diagnosed with cystic fibrosis.
Not a fit: Patients who do not have cystic fibrosis or are not in the young child age group may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to better long-term sinus health and improved quality of life for young children with cystic fibrosis by guiding early treatment decisions.
How similar studies have performed: While HEMT has shown some success in improving sinus issues in adults with CF, its impact on olfactory dysfunction and complete resolution of sinus disease in young children is a new area of focus.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Beswick, Daniel M — University of California Los Angeles
- Study coordinator: Beswick, Daniel M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.