Understanding sexual health issues in women after radiation treatment for pelvic cancers

Novel Functional Anatomic and Biomarker Indices of Radiation-Induced Female Sexual Toxicities in a Multi-Center Cohort

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-10918316

This study is looking at the sexual health issues that women experience after radiation treatment for pelvic cancers, aiming to understand how radiation affects their bodies and to find better ways to help them feel better and enjoy a good quality of life.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10918316 on NIH RePORTER

What this research studies

This research investigates the sexual health challenges faced by women who have undergone radiation therapy for pelvic cancers. It aims to identify the anatomical and biological factors that contribute to sexual dysfunction in these patients, focusing on the impact of radiation on female erectile tissues and the vaginal microbiome. By analyzing a multi-center cohort of female cancer survivors, the study seeks to develop better classifications of radiation toxicity and improve supportive therapies to enhance quality of life. The findings could lead to more effective interventions for managing sexual health in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who have been treated for pelvic cancers and have received radiation therapy.

Not a fit: Patients who have not undergone radiation therapy or do not have pelvic cancers may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments and support for female cancer survivors experiencing sexual dysfunction after radiation therapy.

How similar studies have performed: While there has been some exploration of sexual dysfunction in cancer survivors, this specific approach focusing on radiation-induced effects in female patients is relatively novel.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Radiation Syndrome
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.