NIH-funded research NIH-funded research

Understanding sex differences in heart disease risk for people with diabetes

Official title: Project 3 Yoshida

Funded at Tulane University of Louisiana · NIH-11017009 · Data updated 2026-11-12

This study is looking at how being a woman or a man with type 2 diabetes affects the chances of developing heart disease, especially since younger women with diabetes seem to be at greater risk, and it aims to find ways to better predict and prevent these heart issues.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionTulane University of Louisiana
NIH-funded
Lab location1 site (New Orleans, United States)
Project startFebruary 1, 2024
Project endDecember 31, 2028
Funding year2025
Award (this year)$270,401
NIH project number5P20GM152305-02
Project IDNIH-11017009 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include women and men with early-onset type 2 diabetes, particularly those experiencing obesity-related health issues.

Less likely to help

Patients with late-onset type 2 diabetes or those without significant cardiovascular risk factors may not benefit from this research.

What this research studies

This research aims to explore how sex disparities affect the risk of cardiovascular disease (CVD) in individuals with type 2 diabetes (T2D). It focuses on understanding why women with early-onset T2D face a higher risk of CVD compared to men, particularly as obesity rates rise among younger populations. The study will utilize advanced machine learning techniques to analyze data and improve predictions of cardiovascular risks based on sex-specific factors. By examining the life-course perspective of diabetes and its complications, the research seeks to provide insights that could lead to better prevention and treatment strategies.

Why it matters

Potential benefit: If successful, this research could lead to improved risk prediction and tailored prevention strategies for cardiovascular disease in women with diabetes.

How similar studies have gone: Previous research has shown promise in using machine learning to predict complications in diabetes, but this specific focus on sex disparities is relatively novel.

Where this research is happening

  • Tulane University of Louisiana
    New Orleans, United States
    Active

Researchers

  • Principal investigator: Yoshida, Yilin X — Tulane University of Louisiana
  • Study coordinator: Yoshida, Yilin X

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.