Understanding sex differences in heart and metabolic diseases
Human Translational Bioinformatics Core
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10919850
This study is looking at how heart and metabolic diseases can affect men and women differently, using special mice and lab tests, to help find better ways to treat these conditions for everyone.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10919850 on ClinicalTrials.gov |
What this research studies
This research investigates how sex differences affect cardiometabolic diseases and their risk factors by using genetically modified mouse models and cell-based experiments. The Human Translational Bioinformatics Core will analyze data to translate findings from these models to human populations, focusing on identifying relevant biomarkers and genetic factors. The research aims to enhance our understanding of how these diseases manifest differently in men and women, potentially leading to more personalized treatment approaches.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a history of cardiometabolic diseases or those at risk due to genetic factors.
Not a fit: Patients without any cardiometabolic conditions or risk factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for cardiometabolic diseases tailored to individual patients based on their sex.
How similar studies have performed: Previous research has shown success in using bioinformatics to identify biomarkers in cardiometabolic diseases, indicating that this approach has potential for impactful findings.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ALLAYEE, HOOMAN — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: ALLAYEE, HOOMAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Candidate Disease Gene, Cardiometabolic Disease, Cardiometabolic Disorder