Understanding severe COVID-19 illness in children
COVID-19 Network of Networks Expanding Clinical and Translational approaches to Predict Severe Illness in Children (CONNECT to Predict SIck Children)
This study looks at how COVID-19 affects children in different ways, from mild to serious cases, and aims to find out which kids might be at higher risk for severe illness so that we can better support and protect them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project ID | NIH-10847827 on NIH RePORTER |
What this research studies
This research investigates the wide range of clinical presentations of COVID-19 in children, from mild symptoms to severe conditions like Multisystem Inflammatory Syndrome in Children (MIS-C). By integrating data from over 15 million children, the project aims to identify clinical, social, and biological factors that predict severe illness. The approach combines clinical, epidemiological, genetic, and immunological data to better understand which children are at the highest risk for severe outcomes. This comprehensive analysis will help target interventions for those most vulnerable.
Who could benefit from this research
Good fit: Ideal candidates for this research include children who have been infected with SARS-CoV-2 or are at risk of severe illness from COVID-19.
Not a fit: Patients who are not children or those who have not been exposed to SARS-CoV-2 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prediction and prevention strategies for severe COVID-19 illness in children.
How similar studies have performed: Other research has shown success in using integrated data approaches to predict health outcomes, making this a promising continuation of those efforts.
Where this research is happening
Newark, UNITED STATES
- Rutgers Biomedical and Health Sciences — Newark, United States (Active)
Researchers
- Principal investigator: Kleinman, Lawrence C — Rutgers Biomedical and Health Sciences
- Study coordinator: Kleinman, Lawrence C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.