Understanding severe COVID-19 illness in children
COVID-19 Network of Networks Expanding Clinical and Translational approaches to Predict Severe Illness in Children (CONNECT to Predict SIck Children)
['FUNDING_OTHER'] · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · NIH-10733696
This study looks at how COVID-19 affects children in different ways, from mild to serious cases, and aims to find out which kids might be at higher risk for severe illness so that we can better support them.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RUTGERS BIOMEDICAL AND HEALTH SCIENCES (nih funded) |
| Locations | 1 site (Newark, UNITED STATES) |
| Trial ID | NIH-10733696 on ClinicalTrials.gov |
What this research studies
This research investigates the wide range of clinical presentations of COVID-19 in children, from mild symptoms to severe conditions like Multisystem Inflammatory Syndrome in Children (MIS-C). By analyzing data from over 15 million children, the study aims to identify clinical, social, and biological factors that predict severe illness. The approach integrates various data types, including clinical, epidemiological, and genetic information, to better understand which children are at the highest risk. This comprehensive analysis will help target interventions for those most vulnerable to severe outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include children aged 0-21 who have been exposed to or infected with SARS-CoV-2.
Not a fit: Patients who are adults or those with no history of COVID-19 exposure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved identification and protection of children at risk for severe COVID-19 illness.
How similar studies have performed: Other research has shown success in using integrated data approaches to predict health outcomes, suggesting this methodology could be effective.
Where this research is happening
Newark, UNITED STATES
- RUTGERS BIOMEDICAL AND HEALTH SCIENCES — Newark, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KLEINMAN, LAWRENCE C — RUTGERS BIOMEDICAL AND HEALTH SCIENCES
- Study coordinator: KLEINMAN, LAWRENCE C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: acute disease/disorder, acute disorder, Acute Disease