Understanding Sepsis in Critically Ill Children
Collaborative Pediatric Critical Care Research Network - Clinical Site
This project helps us learn more about how to treat children who get very sick with infections, especially sepsis, to help them recover better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11180282 on NIH RePORTER |
What this research studies
This grant establishes two hospitals, UPMC Children’s Hospital of Pittsburgh and Mercy Children’s Hospital Kansas City, as part of a larger network focused on critically ill children. The first major effort will be a study on sepsis, a severe infection where the body's response can harm organs. We will collect blood samples from children with sepsis to understand how their immune system is fighting the infection and managing inflammation. This information will help us explore new ways to personalize treatments and improve their chances of survival.
Who could benefit from this research
Good fit: Children aged 0-11 years old who are critically ill with sepsis may be candidates for future participation.
Not a fit: Patients who are not children, do not have sepsis, or are not critically ill would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more effective, personalized treatments for children with sepsis, potentially saving lives and improving recovery.
How similar studies have performed: This approach uses new technology to temper the body's response to sepsis, representing a novel strategy not previously available.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Carcillo, Joseph a — University of Pittsburgh at Pittsburgh
- Study coordinator: Carcillo, Joseph a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.