Understanding Sepsis and Inflammation
CORE C - Infection and Inflammation Core
This core facility helps researchers better understand how the body responds to severe infections like sepsis by studying blood samples.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sanford Burnham Prebys Medical Discovery Institute NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11110307 on NIH RePORTER |
What this research studies
This core facility provides essential support for projects focused on sepsis, a life-threatening response to infection. Researchers use this core to plan and carry out studies involving people with sepsis, analyzing their blood samples to track changes in inflammation and other biological markers. By comparing these markers, the core helps uncover different ways sepsis affects the body, which can vary depending on the type of infection. This work aims to deepen our understanding of how proteins in the blood change during sepsis and how these changes contribute to the disease.
Who could benefit from this research
Good fit: This core supports research that may involve individuals experiencing sepsis or those who have recovered from it, as well as healthy volunteers who might donate blood samples for comparison.
Not a fit: Patients not directly involved in the specific sepsis cohort studies supported by this core would not receive direct benefit from this particular grant.
Why it matters
Potential benefit: This work could lead to a better understanding of sepsis, potentially helping to identify new ways to diagnose and treat this serious condition.
How similar studies have performed: The core has successfully developed and published standardized methods for studying sepsis in models, which supports the reliability of its analytical approaches for human samples.
Where this research is happening
La Jolla, United States
- Sanford Burnham Prebys Medical Discovery Institute — La Jolla, United States (Active)
Researchers
- Principal investigator: Marth, Jamey — Sanford Burnham Prebys Medical Discovery Institute
- Study coordinator: Marth, Jamey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.