Understanding seizures after brain injuries
Acute neural injury and posttraumatic epilepsy
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA RIVERSIDE · NIH-11110443
This study is looking at how and why some people develop seizures after a brain injury, aiming to find out which parts of the brain are affected and how they change, so we can improve ways to prevent or treat these seizures.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA RIVERSIDE (nih funded) |
| Locations | 1 site (RIVERSIDE, UNITED STATES) |
| Trial ID | NIH-11110443 on ClinicalTrials.gov |
What this research studies
This research investigates posttraumatic epilepsy (PTE), which involves chronic seizures that can occur after a traumatic brain injury (TBI). The study aims to identify the specific brain areas where PTE develops and the physiological changes that occur in these regions. By using advanced techniques like multielectrode array electroencephalography (EEG), researchers will analyze the cellular and molecular alterations that contribute to the emergence of seizure foci in the brain. This research could lead to a better understanding of how to prevent or treat seizures following brain injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a traumatic brain injury and are at risk of developing posttraumatic epilepsy.
Not a fit: Patients who have not experienced a traumatic brain injury or those with pre-existing seizure disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from seizures after traumatic brain injuries.
How similar studies have performed: Previous research has shown promising results in understanding the mechanisms of posttraumatic epilepsy, but this specific approach is novel and aims to provide deeper insights.
Where this research is happening
RIVERSIDE, UNITED STATES
- UNIVERSITY OF CALIFORNIA RIVERSIDE — RIVERSIDE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BINDER, DEVIN K — UNIVERSITY OF CALIFORNIA RIVERSIDE
- Study coordinator: BINDER, DEVIN K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.