Understanding Schizophrenia Genes in South African Xhosa People
1/3 Genomics of Schizophrenia in the South African Xhosa
This project aims to learn more about the genetic factors that contribute to schizophrenia in people of Xhosa ancestry in South Africa.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11013881 on NIH RePORTER |
What this research studies
We are working with Xhosa-speaking individuals in South Africa to better understand the genetic causes of schizophrenia. Our team collects genetic information from people with schizophrenia and compares it to those without the condition. This helps us find specific genetic differences that might play a role in developing schizophrenia. By studying a population with diverse genetic backgrounds, we hope to uncover new insights into this complex condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are Xhosa-speaking individuals in South Africa, both those living with schizophrenia and those who do not have the condition.
Not a fit: Patients who are not of Xhosa ancestry or do not reside in South Africa may not directly benefit from participation in this specific genetic research.
Why it matters
Potential benefit: If successful, this work could lead to a better understanding of schizophrenia, potentially paving the way for new ways to prevent, diagnose, or treat the condition.
How similar studies have performed: An initial study in this population successfully identified rare genetic mutations linked to schizophrenia, building on previous findings in other populations.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: King, Mary-Claire — University of Washington
- Study coordinator: King, Mary-Claire
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.