Understanding resilience in people with opioid use disorder
A Novel Human Laboratory Model of Resilience Among Individuals with Opioid Use Disorder
['FUNDING_CAREER'] · JOHNS HOPKINS UNIVERSITY · NIH-10808410
This study is looking for people with opioid use disorder to stay in a safe setting for 10 days, where they’ll take oral morphine and help researchers learn more about how being resilient can influence their choices and behaviors, with the hope of finding better ways to treat this condition.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10808410 on ClinicalTrials.gov |
What this research studies
This research aims to develop a laboratory model to study resilience among individuals with opioid use disorder (OUD). Participants who meet the criteria for OUD will be stabilized on oral morphine during a 10-day inpatient stay, allowing researchers to examine their behaviors related to resilience in a controlled environment. The study will utilize various psychological and cognitive assessments to better understand how resilience affects decision-making and heroin-seeking behaviors. By focusing on resilience, the research seeks to uncover new insights that could lead to improved treatment strategies for OUD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who meet the DSM-5 criteria for opioid use disorder.
Not a fit: Patients who do not have opioid use disorder or those who are not willing to participate in an inpatient setting may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to enhanced treatment approaches that leverage resilience to improve outcomes for individuals with opioid use disorder.
How similar studies have performed: While resilience has been studied in various contexts, this specific laboratory model for opioid use disorder is a novel approach that has not been extensively tested.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MARTINEZ, SUKY — JOHNS HOPKINS UNIVERSITY
- Study coordinator: MARTINEZ, SUKY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.