Understanding Resilience in Opioid Use Disorder
A Novel Human Laboratory Model of Resilience Among Individuals with Opioid Use Disorder
['FUNDING_CAREER'] · JOHNS HOPKINS UNIVERSITY · NIH-11118814
This project explores how personal strengths, or resilience, might help people with opioid use disorder manage cravings and make healthy choices.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11118814 on ClinicalTrials.gov |
What this research studies
We are looking for ways to understand why some people with opioid use disorder are better able to cope with challenges and avoid relapse. This project brings together 50 individuals with opioid use disorder for a 10-day inpatient stay, where they will receive stable medication. During this time, we will use special tasks and tests to measure their resilience, how they make decisions, and their responses to stress. Our goal is to see if these resilience measures connect to behaviors like drug-seeking.
Who could benefit from this research
Good fit: Individuals who have been diagnosed with opioid use disorder and are willing to participate in a 10-day inpatient program may be ideal candidates.
Not a fit: Patients seeking immediate treatment for opioid use disorder may not directly benefit from participating in this foundational research.
Why it matters
Potential benefit: If successful, this work could help us better understand the factors that protect individuals from relapse and inform the development of new, personalized treatments for opioid use disorder.
How similar studies have performed: While the concept of resilience in addiction is recognized, this project aims to develop a novel laboratory model to objectively measure it.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MARTINEZ, SUKY — JOHNS HOPKINS UNIVERSITY
- Study coordinator: MARTINEZ, SUKY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.