Understanding reduced blood flow in the brain related to frontotemporal dementia.
Investigating the cause of cerebral blood flow reductions in a mouse model of frontotemporal dementia
This study is looking at how blood flow to the brain changes in mice with frontotemporal dementia, hoping to find ways to improve brain health for people with this condition.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami Coral Gables NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-10701298 on NIH RePORTER |
What this research studies
This research investigates how blood flow to the brain is affected in a mouse model of frontotemporal dementia. By examining the underlying mechanisms that lead to reduced cerebral blood flow, the study aims to identify potential pathways that could be targeted for therapeutic interventions. The approach involves using advanced imaging techniques and physiological assessments to gather data on blood circulation in the brain. Insights gained from this research may help in developing strategies to improve brain health in patients with frontotemporal dementia.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with frontotemporal dementia or those at risk of developing this condition.
Not a fit: Patients with other types of dementia or neurological disorders unrelated to frontotemporal dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance blood flow to the brain, potentially improving cognitive function in patients with frontotemporal dementia.
How similar studies have performed: While there has been research on cerebral blood flow in various types of dementia, this specific investigation in a mouse model of frontotemporal dementia is relatively novel.
Where this research is happening
Coral Gables, United States
- University of Miami Coral Gables — Coral Gables, United States (Active)
Researchers
- Principal investigator: Bracko, Oliver — University of Miami Coral Gables
- Study coordinator: Bracko, Oliver
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.