Understanding recovery after stroke in patients with cerebral amyloid angiopathy
Ischemic Stroke in Cerebral Amyloid Angiopathy: Microvascular Injury and Recovery
This study is looking at how having a condition called cerebral amyloid angiopathy (CAA) affects recovery after an ischemic stroke, and it aims to find ways to help improve healing for stroke survivors with this condition.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-10848399 on NIH RePORTER |
What this research studies
This research investigates how ischemic stroke affects recovery in patients with cerebral amyloid angiopathy (CAA), a condition characterized by the buildup of amyloid proteins in the brain's blood vessels. The study aims to explore the mechanisms that lead to delayed recovery of motor and cognitive functions after a stroke, particularly in those with CAA. By using a specialized mouse model, researchers will examine the relationship between amyloid accumulation and the health of blood vessels, which is crucial for brain recovery. The goal is to identify potential targeted therapies that could improve outcomes for stroke survivors.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced an ischemic stroke and have been diagnosed with cerebral amyloid angiopathy.
Not a fit: Patients who have not had a stroke or do not have cerebral amyloid angiopathy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance recovery for stroke patients with cerebral amyloid angiopathy.
How similar studies have performed: While the specific focus on CAA and ischemic stroke recovery is relatively novel, previous research has shown promising results in understanding stroke recovery mechanisms.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Colbert, Olivia Marlowe — University of Miami School of Medicine
- Study coordinator: Colbert, Olivia Marlowe
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.