Understanding Rare Liver Conditions in Children

Advancing our Understanding of Rare Pediatric Liver Diseases

['FUNDING_U01'] · CHILDREN'S HOSP OF PHILADELPHIA · NIH-11124874

This effort brings together experts to learn more about rare liver conditions affecting children, aiming to find better ways to care for them.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorCHILDREN'S HOSP OF PHILADELPHIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-11124874 on ClinicalTrials.gov

What this research studies

For over twenty years, a network of hospitals has been working together to understand rare liver conditions in children. This collaboration has built a valuable database and collection of biological samples to help researchers. By continuing to work together, we hope to uncover the causes, natural progression, and best treatment options for these complex diseases. Our goal is to improve the quality and effectiveness of care for all children living with these conditions.

Who could benefit from this research

Good fit: This research is relevant for children aged 0-11 years old who have been diagnosed with rare cholestatic pediatric liver diseases, such as biliary atresia.

Not a fit: Adults or individuals without these specific rare pediatric liver conditions would not directly benefit from this particular research opportunity.

Why it matters

Potential benefit: If successful, this work could lead to a deeper understanding of rare pediatric liver diseases, resulting in more effective treatments and improved care for affected children.

How similar studies have performed: This effort builds upon twenty years of coordinated investigations by the Childhood Liver Disease Research Network, which has already advanced understanding of these disorders.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.