Understanding rare human cancers by studying tumors in mammals
Leveraging Mammalian Cancers, Platinum-Quality Genome Assemblies, and Large-Scale Data to Identify Mechanisms of Rare Human Cancers
This study is looking at how rare cancers develop by comparing cancer data from different animals, hoping to find new ways to understand and treat these cancers in people like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10895334 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind rare human cancers by analyzing cancer data from various mammalian species. By creating a comprehensive database of tumors found in mammals and applying advanced machine learning techniques, the study aims to uncover patterns of cancer emergence and resistance. This approach allows researchers to link genomic information from both human and non-human mammals, potentially leading to new insights into cancer biology and treatment options. Patients may benefit from the findings that could inform future therapies and early diagnosis strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with rare cancers, particularly those under 21 years old.
Not a fit: Patients with common cancers or those not diagnosed with cancer may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new discoveries that improve the understanding and treatment of rare human cancers.
How similar studies have performed: Other research has shown promise in using comparative oncology approaches, suggesting potential for success in this novel investigation.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Graim, Kiley — University of Florida
- Study coordinator: Graim, Kiley
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.