Understanding Radiation for Prostate Cancer with Limited Spread
Official title: Radiation Oncology-Biology Integration Network on Oligometastasis (ROBIN OligoMET) Center
Funded at University of Maryland Baltimore · NIH-11171427 · Data updated 2026-11-12
This research brings together experts to learn how radiation therapy can help patients with prostate cancer that has spread to only a few spots.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | August 4, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $1,505,442 |
| NIH project number | 5U54CA273956-04 |
| Project ID | NIH-11171427 on NIH RePORTER |
Who could benefit from this research
✓Could help
This research is most relevant to patients with prostate cancer that has spread to a limited number of new locations in the body.
✕Less likely to help
Patients whose prostate cancer has not spread or has spread widely to many areas may not directly benefit from this specific research focus.
What this research studies
When prostate cancer spreads, it can sometimes go to just a few new areas, a stage called oligometastasis. This project aims to understand how radiation therapy works at the cell, tissue, and organ levels to fight this limited spread. Researchers will use information from clinical trials, biological samples, and advanced computer models to explore these mechanisms. The goal is to discover new and better ways to use radiation to stop prostate cancer from spreading further.
Why it matters
Potential benefit: If successful, this work could lead to improved radiation treatments that more effectively control or prevent the spread of prostate cancer.
How similar studies have gone: Small randomized studies have shown some success with radiation in recurrent limited spread, but its use in newly diagnosed limited spread is still being explored.
Where this research is happening
-
University of Maryland Baltimore
Baltimore, United States Active
Researchers
- Principal investigator: Sawant, Amit — University of Maryland Baltimore
- Study coordinator: Sawant, Amit
Related research
Other NIH-funded projects on the same topics.
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ROBIN OligoMET Center: Radiation and Biology Insights for Prostate Cancer Metastasis
A nationwide collaboration is testing how targeted radiation can alter the spread of prostate cancer that has few metastases, with the goal of improving control of the disease.
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Investigating how radiation therapy can improve treatment for limited metastatic prostate cancer.
This study is looking at how radiation therapy can help men with prostate cancer that has spread to a few places in the body, aiming to see if it can stop the cancer from getting worse and improve treatment options for patients.
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Adding targeted stereotactic body radiation therapy to standard systemic treatment for people with oligometastatic urothelial (bladder) carcinoma.
This study will test whether adding stereotactic body radiation therapy (SBRT) to usual systemic treatment helps people with urothelial (bladder) cancer who have up to three extracranial metastases.
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Stereotactic body radiotherapy for extracranial oligometastatic breast cancer
This project sees if stereotactic body radiotherapy (SBRT) helps control cancer and extend survival in adults with extracranial oligometastatic breast cancer.
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Stereotactic body radiotherapy (SABR) for limited metastases
This program tries stereotactic body radiotherapy (SABR) in people with up to five oligometastatic or oligoprogressive cancer lesions to see if it controls disease better, affects symptoms and side effects, and changes ctDNA in the blood.
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Immediate simulation-free SBRT for people with up to five metastatic tumors
This tests whether giving stereotactic body radiation therapy (SBRT) right away without a separate CT simulation helps people with up to five metastatic cancer spots get treatment faster.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.