Understanding pulmonary hypertension caused by left heart disease
Pulmonary Hypertension in Left Heart Disease
This study is looking at how problems with the left side of the heart can cause high blood pressure in the lungs and issues with the right side of the heart, and it aims to find better ways to treat patients by understanding their unique conditions and the biological processes involved.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11111177 on NIH RePORTER |
What this research studies
This research investigates how left heart disease leads to pulmonary hypertension and right ventricular failure. It aims to identify the specific mechanisms and classifications of pulmonary vascular disease associated with this condition. By using advanced hemodynamic assessments, the study will categorize patients based on their unique vascular responses, which could help tailor more effective treatments. The research also seeks to explore the biological pathways involved in pulmonary vascular disease to improve therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with left heart disease who are experiencing pulmonary hypertension.
Not a fit: Patients with pulmonary hypertension not related to left heart disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients suffering from pulmonary hypertension due to left heart disease.
How similar studies have performed: Previous research on pulmonary hypertension has shown promising results, but this approach to specifically address left heart disease is relatively novel.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Redfield, Margaret M — Mayo Clinic Rochester
- Study coordinator: Redfield, Margaret M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.