Understanding proteins that help cells move during development
Characterization of two proteins that regulate vertebrate
This study looks at how specific proteins help cells move and organize during the early stages of development, which could help us understand issues like birth defects and cancer spread.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Temple Univ of the Commonwealth NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10690706 on NIH RePORTER |
What this research studies
This research investigates how certain proteins influence the movement of cells during embryonic development, particularly focusing on the Wnt signaling pathway. By studying the interactions between these proteins and their role in cellular polarization, the research aims to uncover mechanisms that could lead to birth defects and cancer metastasis. The approach includes isolating and characterizing new binding partners for a key protein involved in this signaling pathway, which may provide insights into how cells migrate and organize during critical developmental stages.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with congenital abnormalities or those at risk for conditions influenced by cell migration during development.
Not a fit: Patients with conditions unrelated to cellular motility or those who do not have congenital abnormalities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potential treatments for birth defects and cancers related to cell migration.
How similar studies have performed: Other research has shown promising results in understanding the Wnt signaling pathway and its implications in developmental biology and cancer, indicating that this approach has potential for success.
Where this research is happening
Philadelphia, United States
- Temple Univ of the Commonwealth — Philadelphia, United States (Active)
Researchers
- Principal investigator: Habas, Raymond — Temple Univ of the Commonwealth
- Study coordinator: Habas, Raymond
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.