Understanding protein markers for prostate cancer risk in men of African and European descent
Uncovering causal protein markers to improve prostate cancer etiology understanding and risk prediction in Africans and Europeans
This project aims to find specific protein markers in the blood that can help us better understand prostate cancer and predict who might be at higher risk, especially for men of African and European backgrounds.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Hawaii at Manoa NIH-funded |
| Lab location | 1 site (Honolulu, United States) |
| Project ID | NIH-11125805 on NIH RePORTER |
What this research studies
Prostate cancer affects men differently across various ancestries, and we don't fully understand why some men develop aggressive forms. This project focuses on identifying key proteins in the blood that play a direct role in prostate cancer development. By looking at these proteins in both African and European men, we hope to uncover new insights into the disease's causes. The goal is to create better tools for predicting a man's risk of prostate cancer and its aggressive forms.
Who could benefit from this research
Good fit: This research is relevant to men, particularly those of African and European ancestry, who are concerned about prostate cancer risk or have a family history of the disease.
Not a fit: Patients already diagnosed with prostate cancer may not directly benefit from this specific research, as it focuses on risk prediction and understanding disease causes rather than treatment.
Why it matters
Potential benefit: If successful, this work could lead to more accurate ways to identify men at high risk for prostate cancer, allowing for earlier detection and potentially more effective treatment strategies.
How similar studies have performed: While previous studies have identified many potential protein markers, this project uses a novel approach to overcome past limitations and clarify which markers are truly causal and relevant across different ancestries.
Where this research is happening
Honolulu, United States
- University of Hawaii at Manoa — Honolulu, United States (Active)
Researchers
- Principal investigator: Wu, Lang — University of Hawaii at Manoa
- Study coordinator: Wu, Lang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.